ENIn the article the known portrait of Francisk Skorina from 1517 and the included text elements (parenthesis) and musca depicta is examined primarily with help of semiological analysis. Although there is a large amount of literature about the publisher’s portrait, it has not been studied within the most obvious and obligatory genre paradigm – the European and in particular Czech Portrait paintings of the first quarter of the 16th century. The Skoryna’s portrait is the second precisely dated Czech portrait in the Renaissance period and the first portrait of a bourgeoisie representative. Keywords: Francisk Skorina, 1517 portrait, trompe-lʼœil, musca depicta, biblical illustration, Master of the Litoměřice Altarpiece. [From the publication]